Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860880 | 0.91 | TLR7 (0.86) | TLR7TLR8 | |
| SCHEMBL860879 | 0.91 | TLR7 (0.86) | TLR7TLR8 | |
| SCHEMBL8532398 | 0.90 | TLR7 (0.81) | TLR7TLR8 | |
| SCHEMBL8775090 | 0.89 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL8546752 | 0.88 | TLR7 (0.79) | TLR7TLR8 | |
| SCHEMBL4201920 | 0.88 | TLR7 (0.87) | TLR7TLR8 | |
| SCHEMBL4201925 | 0.88 | TLR7 (0.87) | TLR7TLR8 | |
| SCHEMBL12343249 | 0.88 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL8521010 | 0.87 | TLR8 (0.89) | TLR7TLR8 | |
| SCHEMBL15305567 | 0.87 | TLR7 (0.80) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066335-A1 | PHENOL COMPOUNDS ALS TOLL -LIKE RECEPTOR 7 AGONISTS | ASTRAZENECA AB (SE) | 2012-05-24 | — | — | WO | disclosed |
| WO-2012066336-A1 | BENZYLAMINE COMPOUNDS AS TOLL -LIKE RECEPTOR 7 AGONISTS | ASTRAZENECA AB (SE) | 2012-05-24 | — | — | WO | disclosed |