Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | ANPEP | P15144 | 2/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | LAP3 | P28838 | 3/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27712365 | 1.00 | EPHX1 (0.59) | EPHX1ANPEPALPIPKMPTGS1 | |
| SCHEMBL6033692 | 1.00 | EPHX1 (0.59) | EPHX1ANPEPALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL29410716 | 0.98 | EPHX1 (0.57) | EPHX1ANPEPALPIPKMPTGS1 | |
| SCHEMBL8748122 | 0.83 | TAAR1 (0.50) | SLC7A5SLC6A2TAAR1 | |
| SCHEMBL18167808 | 0.82 | EPHX1 (0.61) | EPHX1ANPEPALPIPKMPTGS1 | |
| SCHEMBL18167806 | 0.82 | EPHX1 (0.61) | EPHX1ANPEPALPIPKMPTGS1 | |
| SCHEMBL27700316 | 0.81 | ANPEP (0.50) | EPHX1ANPEP | |
| SCHEMBL27720875 | 0.81 | EPHX1 (0.55) | EPHX1ANPEPALPIPKMPTGS1 | |
| SCHEMBL352772 | 0.81 | EPHX1 (0.55) | EPHX1ANPEPALPIPKMPTGS1 | |
| SCHEMBL27700318 | 0.81 | EPHX1 (0.55) | EPHX1ANPEPALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101103969-A | Therapeutic formulations for the treatment of beta-amyloid related diseases | NEUROCHEM INTERNAT LTD (CH) | 2008-01-16 | — | — | CN | disclosed |
| EP-0460679-B1 | Endothelin antagonistic peptide derivatives | BANYU PHARMA CO LTD (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5691315-A | CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5470833-A | Vasodilators, bronchodilators | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5444152-A | Vasolidator or bronchodilator | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| EP-0460679-A2 | Endothelin antagonistic peptide derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |