Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527603 | 0.90 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL7903617 | 0.83 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL917087 | 0.83 | SRD5A1 (0.52) | SRD5A1SRD5A2 | |
| SCHEMBL917025 | 0.82 | SRD5A1 (0.52) | SRD5A1SRD5A2 | |
| SCHEMBL917162 | 0.81 | SRD5A1 (0.52) | SRD5A1SRD5A2 | |
| SCHEMBL917432 | 0.81 | SRD5A1 (0.50) | SRD5A1SRD5A2 | |
| SCHEMBL915553 | 0.81 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL915495 | 0.81 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL917935 | 0.81 | SRD5A1 (0.52) | SRD5A1SRD5A2 | |
| SCHEMBL917085 | 0.81 | SRD5A1 (0.52) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739137-A | 16-substituted-4-aza-3-oxo-androstane as 5-alpha-reductase isozyme 1 inhibitors | MERCK & CO., INC. (US) | 1998-04-14 | — | — | US | disclosed |