SCHEMBL852758

SCHEMBL852758

CC(C)(C)CCC(=O)Oc1ccc(O)c(C(C)(C)C)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 7/20 0.53
ATM Q13315 2/20 0.53
GAA P10253 2/20 0.52
XBP1 P17861 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MAPT P10636 2/20 0.51
POLB P06746 1/20 0.51
ALDH1A1 P00352 4/20 0.50
ESRRA P11474 3/20 0.50
LMNA P02545 2/20 0.42
HTT P42858 2/20 0.42
HSD17B10 Q99714 2/20 0.42
NR1I2 O75469 1/20 0.42
CYP2C9 P11712 1/20 0.42
MIF P14174 1/20 0.42
TYR P14679 1/20 0.42
ALOX15 P16050 1/20 0.42
NFE2L2 Q16236 1/20 0.42
HSP90AA1 P07900 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6130581 1.00 NR1H4 (0.53) NR1H4ATMGAAXBP1NPSR1
SCHEMBL6897902 0.87 TDP1 (0.42) NR1H4ATMGAAXBP1NPSR1
SCHEMBL3686615 0.87 ATM (0.60) NR1H4ATMGAAXBP1NPSR1
SCHEMBL29268232 0.84 ATM (0.64) NR1H4ATMGAAXBP1NPSR1
SCHEMBL5062825 0.83 ATM (0.59) NR1H4ATMGAAXBP1NPSR1
SCHEMBL29563822 0.83 ATM (0.59) NR1H4ATMGAAXBP1NPSR1
SCHEMBL29160643 0.83 NR1H4 (0.51) NR1H4ATMGAAXBP1NPSR1
SCHEMBL27489025 0.83 ATM (0.63) NR1H4ATMGAAXBP1NPSR1
SCHEMBL22605984 0.82 NR1H4 (0.56) NR1H4ATMGAAXBP1NPSR1
SCHEMBL11783407 0.82 ATM (0.62) NR1H4ATMGAAXBP1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0905180-B1 Dust free stabiliser granules containing epoxide and process of their preparation CIBA SC HOLDING AG (CH) 2003-05-21 EP claimed
EP-1458838-B1 LUBRICATING OIL HAVING ENHANCED RESISTANCE TO OXIDATION, NITRATION AND VISCOSITY INCREASE CHEVRON ORONITE CO (US) 2012-03-28 EP disclosed
EP-1451274-A4 LUBRICATING OIL ADDITIVE SYSTEM PARTICULARLY USEFUL FOR NATURAL GAS FUELED ENGINES CHEVRON ORONITE CO (US) 2005-03-16 EP disclosed
EP-1458838-A4 LUBRICATING OIL HAVING ENHANCED RESISTANCE TO OXIDATION, NITRATION AND VISCOSITY INCREASE CHEVRON ORONITE CO (US) 2005-03-16 EP disclosed
EP-1458838-A1 LUBRICATING OIL HAVING ENHANCED RESISTANCE TO OXIDATION, NITRATION AND VISCOSITY INCREASE Chevron Oronite Company LLC (US) 2004-09-22 EP disclosed
EP-1451274-A1 LUBRICATING OIL ADDITIVE SYSTEM PARTICULARLY USEFUL FOR NATURAL GAS FUELED ENGINES Chevron Oronite Company LLC (US) 2004-09-01 EP disclosed
WO-2003048282-A1 LUBRICATING OIL HAVING ENHANCED RESISTANCE TO OXIDATION, NITRATION AND VISCOSITY INCREASE CHEVRON ORONITE COMPANY LLC (US) 2003-06-12 WO disclosed
WO-2003048277-A1 LUBRICATING OIL ADDITIVE SYSTEM PARTICULARLY USEFUL FOR NATURAL GAS FUELED ENGINES CHEVRON ORONITE COMPANY LLC (US) 2003-06-12 WO disclosed