Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.80 |
| ▸ | HTT | P42858 | 2/20 | 0.77 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.70 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.50 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.50 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1834847 | 1.00 | USP2 (0.80) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL2996593 | 1.00 | USP2 (0.80) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL10607854 | 1.00 | USP2 (0.80) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL10566561 | 1.00 | USP2 (0.80) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL10605202 | 1.00 | USP2 (0.80) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL1835536 | 1.00 | USP2 (0.80) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL9117095 | 1.00 | USP2 (0.80) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL251104 | 1.00 | USP2 (0.80) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL2853658 | 1.00 | USP2 (0.80) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL28914358 | 1.00 | USP2 (0.80) | USP2HTTLPAR5SPHK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107261148-A | Methylphenidate prodrug, its preparation and application | 凯姆制药公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-103826633-B | Methylphenidate prodrugs, methods of making and using the same | 凯姆制药公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-103826633-A | Methylphenidate prodrugs, methods of making and using the same | KEMPHARM INC | 2014-05-28 | — | — | CN | disclosed |
| EP-0728737-B1 | Quaternary ammonium salt, method for production thereof, and its use within a softener composition | KAO CORP (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5696070-A | HAIR, FABRIC RINSES, SOFTENERS | KAO CORPORATION (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0728737-A1 | Quaternary ammonium salt, method for production thereof, and softener composition using salt | Kao Corporation (JP) | 1996-08-28 | — | — | EP | disclosed |