⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946806 | 1.00 | — | — | |
| SCHEMBL1985953 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28279850 | 0.97 | TP53 (0.43) | — | |
| SCHEMBL28177617 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL28279851 | 0.97 | TP53 (0.43) | — | |
| Isopropylamine SCHEMBL27887484 | 0.80 | SLC22A6 (0.39) | — | |
| SCHEMBL14241198 | 0.79 | TP53 (0.39) | — | |
| SCHEMBL584135 | 0.78 | SLC22A6 (0.37) | — | |
| SCHEMBL26999156 | 0.78 | SLC22A6 (0.37) | — | |
| SCHEMBL27701304 | 0.78 | SLC22A6 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4019528-B1 | BILE ACID DERIVATIVE, COMPOSITION AND APPLICATION THEREOF | SHENZHEN YUNHE PHARMACEUTICAL TECH PARTNERSHIP LIMITED (CN) | 2026-01-28 | — | — | EP | disclosed |
| US-12491190-B2 | Bile acid derivative, composition and application thereof | SHENZHEN YUNHE PHARMACEUTICAL TECHNOLOGY PARTNERSHIP (LIMITED) (CN) | 2025-12-09 | — | — | US | disclosed |
| CN-116925168-A | Bile acid derivatives, compositions and uses thereof | 深圳云合医药科技合伙企业(有限合伙) | 2023-10-24 | — | — | CN | disclosed |
| CN-112409435-B | Bile acid derivatives, compositions and uses thereof | 深圳云合医药科技合伙企业(有限合伙) | 2023-07-18 | — | — | CN | disclosed |
| US-20220273675-A1 | BILE ACID DERIVATIVE, COMPOSITION AND APPLICATION THEREOF | SHENZHEN YUNHE PHARMACEUTICAL TECHNOLOGY PARTNERSHIP (LIMITED) (CN) | 2022-09-01 | — | — | US | disclosed |
| EP-4019528-A1 | BILE ACID DERIVATIVE, COMPOSITION AND APPLICATION THEREOF | Shenzhen Yunhe Pharmaceutical Technology Partnership (Limited) (CN) | 2022-06-29 | — | — | EP | disclosed |
| WO-2021036998-A1 | BILE ACID DERIVATIVE, COMPOSITION AND APPLICATION THEREOF | 深圳云合医药科技合伙企业(有限合伙) | 2021-03-04 | — | — | WO | disclosed |
| CN-112409435-A | Bile acid derivatives, compositions and uses thereof | 深圳云合医药科技合伙企业(有限合伙) | 2021-02-26 | — | — | CN | disclosed |
| EP-0460679-B1 | Endothelin antagonistic peptide derivatives | BANYU PHARMA CO LTD (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5444152-A | Vasolidator or bronchodilator | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |