Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521088 | 0.96 | TLR7 (0.65) | TLR7TLR8 | |
| SCHEMBL8548091 | 0.94 | TLR7 (0.71) | TLR7TLR8 | |
| SCHEMBL8546752 | 0.89 | TLR7 (0.79) | TLR7TLR8 | |
| SCHEMBL8532398 | 0.89 | TLR7 (0.81) | TLR7TLR8 | |
| SCHEMBL4204511 | 0.84 | TLR7 (0.83) | TLR7TLR8 | |
| SCHEMBL4198100 | 0.84 | TLR7 (0.83) | TLR7TLR8 | |
| SCHEMBL8579753 | 0.83 | TLR8 (0.78) | TLR7TLR8 | |
| SCHEMBL8521583 | 0.83 | TLR7 (0.75) | TLR7TLR8 | |
| SCHEMBL12343355 | 0.82 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL8546320 | 0.81 | TLR8 (0.80) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066335-A1 | PHENOL COMPOUNDS ALS TOLL -LIKE RECEPTOR 7 AGONISTS | ASTRAZENECA AB (SE) | 2012-05-24 | — | — | WO | disclosed |