Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 8/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525815 | 1.00 | SLC18A3 (0.75) | SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL8525818 | 1.00 | SLC18A3 (0.75) | SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL8528072 | 1.00 | SLC18A3 (0.75) | SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2 | |
| Benzovesamicol SCHEMBL30774641 | 0.86 | SLC18A3 (1.00) | SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2 | |
| Benzovesamicol SCHEMBL29794132 | 0.86 | SLC18A3 (1.00) | SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL9173091 | 0.81 | SLC18A3 (0.55) | SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL8526424 | 0.79 | SLC18A3 (0.76) | SLC18A3 | |
| SCHEMBL8526426 | 0.79 | SLC18A3 (0.76) | SLC18A3 | |
| SCHEMBL8528762 | 0.78 | SLC18A3 (0.65) | SLC18A3CYP2D6TSHRCYP1A2CYP2C9 | |
| SCHEMBL8528768 | 0.78 | SLC18A3 (0.65) | SLC18A3CYP2D6TSHRCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648130-B1 | RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING | UNIV MICHIGAN (US) | 1998-12-30 | — | — | EP | disclosed |