Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8528372

N=C(N)NCCC[C@H](NC(=O)CC(c1ccccc1)c1ccccc1)C(N)=O.O=C(O)C(F)(F)F

nearest known ligand 0.50

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 8/20 0.50
C3AR1 Q16581 1/20 0.47
PADI1 Q9ULC6 5/20 0.46
PADI4 Q9UM07 5/20 0.46
PADI3 Q9ULW8 4/20 0.46
PADI2 Q9Y2J8 3/20 0.46
TACR1 P25103 4/20 0.46
NPY1R P25929 6/20 0.42
NPY5R Q15761 5/20 0.42
NPY2R P49146 3/20 0.42
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5319184 0.93 C3AR1 (0.52) NPY4RC3AR1PADI1PADI4PADI3
SCHEMBL6801489 0.86 C3AR1 (0.61) C3AR1TACR1LMNAPOLB
Trifluoroacetic Acid SCHEMBL8526497 0.86 NPY1R (0.51) NPY4RPADI1PADI4PADI3PADI2
SCHEMBL9058352 0.84 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2R
SCHEMBL9058204 0.82 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2R
Trifluoroacetic Acid SCHEMBL29785781 0.81 C3AR1 (0.74) NPY4RC3AR1PADI1PADI4PADI3
SCHEMBL9058342 0.81 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2R
SCHEMBL9057977 0.81 NPY4R (0.65) NPY4RNPY1RNPY5RNPY2R
SCHEMBL9058194 0.80 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2R
SCHEMBL1388524 0.78 NPY1R (0.49) NPY4RC3AR1NPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885186-A1 AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM Dr. Karl Thomae GmbH (DE) 1998-12-23 EP disclosed
WO-1997019911-A1 AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM DR. KARL THOMAE GMBH (DE) 1997-06-05 WO disclosed