SCHEMBL8528477

SCHEMBL8528477

COCCCNC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.37
KDM4E B2RXH2 5/20 0.37
KMT2A Q03164 1/20 0.37
TSHR P16473 1/20 0.35
GAA P10253 1/20 0.33
RECQL P46063 1/20 0.32
MPI P34949 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
PKM P14618 1/20 0.31
EPHX2 P34913 1/20 0.31
LMNA P02545 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8376708 0.81 KDM4E (0.47) ALDH1A1KDM4EKMT2ATSHRGAA
SCHEMBL19873268 0.81 KDM4E (0.47) ALDH1A1KDM4EKMT2ATSHRGAA
SCHEMBL8528812 0.81 ANPEP (0.37) ALDH1A1KDM4EKMT2ATSHRGAA
SCHEMBL11411891 0.78 KDM4E (0.42) ALDH1A1KDM4EKMT2ATSHRGAA
SCHEMBL8532523 0.78 ANPEP (0.39) KDM4E
SCHEMBL8530435 0.75 KDM4E (0.33) ALDH1A1KDM4EKMT2A
SCHEMBL5453964 0.75 MPI (0.39) MPI
SCHEMBL6759189 0.75 MPI (0.39) MPI
SCHEMBL1586372 0.75 MPI (0.39) MPI
SCHEMBL565806 0.75 MPI (0.39) MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994549-A Piperidine derivatives and process for their production ALBANY MOLECULAR RESEARCH, INC. (US) 1999-11-30 US disclosed
US-5786468-A NONIONIC SURFACTANTS DERIVED FROM CARBOHYDRATES FOR SHAMPOO, DEODORANTS OR CLEANING COMPOUNDS LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1998-07-28 US disclosed
US-5750733-A Hydroxy containing alkyl glycamides, low foaming detergent compositions comprising such and a process for their manufacture LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1998-05-12 US disclosed
US-5631389-A SUCCINAMIDES WITH SUGAR GROUPS, POLLUTION CONTROL, BIODEGRADABLE LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-05-20 US disclosed