Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPOR | P19235 | 1/20 | 0.32 |
| ▸ | NPY4R | P50391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126826 | 0.94 | CNR1 (0.37) | NPY1RF2CNR1CNR2MAPT | |
| SCHEMBL8120508 | 0.93 | F2 (0.38) | NPY1RF2CNR1CNR2MAPT | |
| SCHEMBL8111890 | 0.93 | NPY1R (0.35) | NPY1RF2CNR1CNR2MAPT | |
| SCHEMBL8124247 | 0.93 | NPY1R (0.42) | NPY1RF2CNR1CNR2NPY4R | |
| SCHEMBL8125954 | 0.92 | CNR1 (0.39) | NPY1RF2CNR1CNR2MAPT | |
| SCHEMBL8127055 | 0.92 | CNR1 (0.39) | NPY1RF2CNR1CNR2MAPT | |
| SCHEMBL8126766 | 0.92 | TDP1 (0.43) | NPY1RF2CNR1CNR2MAPT | |
| SCHEMBL8119276 | 0.92 | MEN1 (0.38) | NPY1RF2CNR1CNR2MAPT | |
| SCHEMBL7037385 | 0.92 | MAPT (0.36) | NPY1RF2CNR1CNR2MAPT | |
| SCHEMBL8126099 | 0.92 | CNR1 (0.42) | NPY1RCNR1CNR2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |