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Sugi Predict / Compounds / SCHEMBL8528636

SCHEMBL8528636

SCHEMBL8528636

CC(C)CN(C(=O)C1CC[C@H]2[C@@H]3CNC4=CC(=O)CC[C@]4(C)[C@@H]3CC[C@]12C)c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SRD5A2 P31213 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8531184 0.92 SRD5A2 (0.68) SRD5A2
SCHEMBL8528500 0.92 SRD5A2 (0.68) SRD5A2
SCHEMBL8529390 0.89 SRD5A2 (0.64) SRD5A2
SCHEMBL8612618 0.89 SRD5A2 (0.82) SRD5A2
SCHEMBL8528578 0.88 SRD5A2 (0.76) SRD5A2
SCHEMBL8528588 0.87 SRD5A2 (0.76) SRD5A2
SCHEMBL8652897 0.87 SRD5A2 (0.65) SRD5A2
SCHEMBL8652896 0.87 SRD5A2 (0.65) SRD5A2
SCHEMBL9192543 0.86 SRD5A2 (0.71) SRD5A2
SCHEMBL9192538 0.86 SRD5A2 (0.71) SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0674651-B1 SUBSTITUTED 6-AZAANDROSTENONES GLAXO WELLCOME INC (US) 1998-10-28 — — EP claimed
US-5708001-A TESTOSTERONE-5A-REDUCTASE INHIBITORS GLAXO WELLCOME INC. (US) 1998-01-13 — — US claimed
WO-1994014833-A2 SUBSTITUTED 6-AZAANDROSTENONES GLAXO WELLCOME INC. (US) 1994-07-07 — — WO claimed
EP-0674651-B1 SUBSTITUTED 6-AZAANDROSTENONES GLAXO WELLCOME INC (US) 1998-10-28 — — EP disclosed
US-5708001-A TESTOSTERONE-5A-REDUCTASE INHIBITORS GLAXO WELLCOME INC. (US) 1998-01-13 — — US disclosed
WO-1994014833-A2 SUBSTITUTED 6-AZAANDROSTENONES GLAXO WELLCOME INC. (US) 1994-07-07 — — WO disclosed