Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528870 | 0.83 | TFPI2 (0.47) | KMT2AMEN1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL8527698 | 0.82 | NPSR1 (0.45) | KMT2AMEN1KDM4EALDH1A1THRB | |
| SCHEMBL887129 | 0.80 | HTT (0.54) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12479933 | 0.80 | KMT2A (0.51) | KMT2AMEN1KDM4EALDH1A1THRB | |
| SCHEMBL8076272 | 0.79 | KMT2A (0.67) | KMT2AMEN1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL13967298 | 0.79 | KMT2A (0.40) | KMT2AMEN1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL8530588 | 0.77 | KDM4E (0.41) | KMT2AMEN1KDM4EALDH1A1THRB | |
| SCHEMBL12481080 | 0.75 | KMT2A (0.38) | KMT2AMEN1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL8532596 | 0.74 | KMT2A (0.49) | KMT2AMEN1L3MBTL1ALDH1A1THRB | |
| SCHEMBL9848044 | 0.74 | KMT2A (0.46) | KMT2AMEN1KDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460679-B1 | Endothelin antagonistic peptide derivatives | BANYU PHARMA CO LTD (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5691315-A | CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5470833-A | Vasodilators, bronchodilators | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5444152-A | Vasolidator or bronchodilator | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |