Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753560 | 0.81 | KDM1A (0.34) | KDM1AKDM1BAHR | |
| SCHEMBL23673189 | 0.81 | KDM1A (0.34) | KDM1AKDM1BAHR | |
| SCHEMBL14956862 | 0.81 | KDM1A (0.34) | KDM1AKDM1BAHR | |
| SCHEMBL8528070 | 0.78 | CYP3A4 (0.41) | AHR | |
| SCHEMBL31110619 | 0.78 | CA1 (0.32) | KDM1AKDM1BAHR | |
| SCHEMBL31302156 | 0.77 | HSD17B10 (0.36) | KDM1AKDM1BAHR | |
| SCHEMBL17649240 | 0.77 | CA1 (0.41) | KDM1AKDM1BAHR | |
| SCHEMBL18302718 | 0.76 | GAA (0.32) | KDM1AKDM1BAHR | |
| SCHEMBL14247166 | 0.76 | NMT1 (0.38) | KDM1AKDM1BAHR | |
| SCHEMBL30543313 | 0.76 | GAA (0.32) | KDM1AKDM1BAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682008-B1 | Substituted 2-chloro-3,4,5-trifluorobenzenes and process for their preparation | CLARIANT GMBH (DE) | 1998-12-30 | — | — | EP | disclosed |
| US-5565612-A | Substituted 2-chloro-3,4,5-trifluorobenzenes and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |
| EP-0682008-A1 | Substituted 2-chloro-3,4,5-trifluorobenzenes and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-15 | — | — | EP | disclosed |