Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712869 | 0.86 | CHRM2 (0.53) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9145091 | 0.85 | CHRM2 (0.46) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| Benzylic Acid SCHEMBL27924962 | 0.69 | CHRM3 (0.51) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL8529194 | 0.69 | CHRM2 (0.86) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9145154 | 0.69 | CHRM2 (0.86) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9146124 | 0.69 | CHRM2 (0.86) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL10817618 | 0.69 | CHRM2 (0.86) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9145694 | 0.67 | CYP2C9 (0.64) | LMNA | |
| SCHEMBL9145687 | 0.67 | CYP2C9 (0.64) | LMNA | |
| SCHEMBL4971345 | 0.66 | CHRNA7 (0.56) | CHRM2CHRM1CHRM3CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648130-B1 | RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING | UNIV MICHIGAN (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0648130-A1 | RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING | THE UNIVERSITY OF MICHIGAN (US) | 1995-04-19 | — | — | EP | disclosed |
| US-5387409-A | Diagnostic imaging agents, e.g. hypoxic tissue; radiotherapy; kits | BRACCO INTERNATIONAL B.V. (NL) | 1995-02-07 | — | — | US | disclosed |
| EP-0648130-A4 | RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING. | UNIV MICHIGAN (US) | 1994-01-26 | — | — | EP | disclosed |
| US-5077035-A | Scintigraphic imaging of brain; Alzheimer*s diagnosis | THE UNIVERSITY OF MICHIGAN (US) | 1991-12-31 | — | — | US | disclosed |
| WO-1991017776-A1 | RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING | THE UNIVERSITY OF MICHIGAN (US) | 1991-11-28 | — | — | WO | disclosed |
| EP-0441491-A1 | Boronic acid adducts of rhenium dioxime and technetium-99M dioxime complexes containing a biochemically active group | BRACCO INTERNATIONAL B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |