Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 7/20 | 0.36 |
| ▸ | F10 | P00742 | 5/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528680 | 0.91 | TDP1 (0.36) | CNR1F2F10PRSS1ITGB3 | |
| SCHEMBL6901612 | 0.88 | CNR1 (0.43) | CNR1ITGB3ITGA2BTDP1KMT2A | |
| SCHEMBL6900316 | 0.88 | CNR1 (0.40) | CNR1F10PRSS1TDP1KMT2A | |
| SCHEMBL1389118 | 0.88 | CNR1 (0.41) | CNR1F10PRSS1TDP1KMT2A | |
| SCHEMBL30905434 | 0.88 | CNR1 (0.41) | CNR1F10PRSS1TDP1KMT2A | |
| SCHEMBL8121296 | 0.87 | F2 (0.38) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL8527214 | 0.87 | CNR1 (0.39) | CNR1F10PRSS1TDP1KMT2A | |
| SCHEMBL7751753 | 0.87 | CNR1 (0.41) | CNR1F10PRSS1TDP1KMT2A | |
| SCHEMBL7750689 | 0.87 | MEN1 (0.42) | CNR1F2F10PRSS1ITGB3 | |
| SCHEMBL4651831 | 0.87 | CNR1 (0.42) | CNR1TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |