Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9186080 | 0.86 | SRD5A2 (0.73) | SRD5A2 | |
| SCHEMBL8612102 | 0.84 | SRD5A2 (0.76) | SRD5A2 | |
| SCHEMBL8612097 | 0.84 | SRD5A2 (0.76) | SRD5A2 | |
| SCHEMBL8611644 | 0.83 | SRD5A2 (1.00) | SRD5A2 | |
| SCHEMBL8532138 | 0.83 | SRD5A2 (1.00) | SRD5A2 | |
| SCHEMBL8378956 | 0.82 | SRD5A2 (1.00) | SRD5A2 | |
| SCHEMBL8612621 | 0.82 | SRD5A2 (1.00) | SRD5A2 | |
| SCHEMBL9296418 | 0.82 | SRD5A2 (0.78) | SRD5A2 | |
| SCHEMBL9285721 | 0.82 | SRD5A2 (0.87) | SRD5A2 | |
| SCHEMBL19544504 | 0.82 | SRD5A2 (1.00) | SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674651-B1 | SUBSTITUTED 6-AZAANDROSTENONES | GLAXO WELLCOME INC (US) | 1998-10-28 | — | — | EP | claimed |
| US-5708001-A | TESTOSTERONE-5A-REDUCTASE INHIBITORS | GLAXO WELLCOME INC. (US) | 1998-01-13 | — | — | US | claimed |
| WO-1994014833-A2 | SUBSTITUTED 6-AZAANDROSTENONES | GLAXO WELLCOME INC. (US) | 1994-07-07 | — | — | WO | claimed |
| EP-0674651-B1 | SUBSTITUTED 6-AZAANDROSTENONES | GLAXO WELLCOME INC (US) | 1998-10-28 | — | — | EP | disclosed |
| US-5708001-A | TESTOSTERONE-5A-REDUCTASE INHIBITORS | GLAXO WELLCOME INC. (US) | 1998-01-13 | — | — | US | disclosed |