Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599540 | 0.87 | MAPT (0.56) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL599541 | 0.85 | MAPT (0.56) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17762970 | 0.84 | MAPT (0.57) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15084997 | 0.84 | MAPT (0.53) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20844615 | 0.83 | MAPT (0.56) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26511150 | 0.81 | MAPT (0.58) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24062789 | 0.80 | MAPT (0.53) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16246602 | 0.80 | MAPT (0.59) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3788954 | 0.80 | MAPT (0.49) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10136194 | 0.79 | MAPT (0.55) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849481-A | Nucleic acid hybridization assays employing large comb-type branched polynucleotides | CHIRON CORPORATION (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0541693-B1 | LARGE COMB-TYPE BRANCHED POLYNUCLEOTIDES | CHIRON CORP (US) | 1998-12-09 | — | — | EP | disclosed |
| US-5710264-A | WITH MULTIFUNCTIONAL NUCLEOTIDE SIDECHAINS WHICH CAN BIND TO SINGLE STRANDED POLYNUCLEOTIDE SEQUENCES, AS AMPLIFIER MOLECULES IN NUCLEIC ACID HYBRIDIZATION ASSAYS | CHIRON CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |
| US-5703218-A | USEFUL IN BIOSYNTHESIS | CHIRON CORPORATION (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0543906-B1 | HYDROXYL-PROTECTING GROUPS ORTHOGONALLY REMOVABLE BY REDUCTION AND THEIR USE IN THE CHEMICAL SYNTHESIS OF OLIGONUCLEOTIDES | CHIRON CORP (US) | 1997-03-26 | — | — | EP | disclosed |
| US-5430138-A | Oligonucleotide biosynthesis | CHIRON CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |
| US-5407795-A | CMV probes for use in solution phase sandwich | CHIRON CORPORATION (US) | 1995-04-18 | — | — | US | disclosed |
| EP-0541693-A4 | LARGE COMB-TYPE BRANCHED POLYNUCLEOTIDES | CHIRON CORP (US) | 1994-07-20 | — | — | EP | disclosed |
| EP-0541693-A1 | LARGE COMB-TYPE BRANCHED POLYNUCLEOTIDES | CHIRON CORPORATION (US) | 1993-05-19 | — | — | EP | disclosed |
| WO-1992002526-A1 | LARGE COMB-TYPE BRANCHED POLYNUCLEOTIDES | CHIRON CORPORATION (US) | 1992-02-20 | — | — | WO | disclosed |