Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PDE7A | Q13946 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713707 | 0.85 | MEN1 (0.68) | MEN1KMT2AMAPTNPSR1APOBEC3G | |
| SCHEMBL29869345 | 0.85 | MEN1 (0.68) | MEN1KMT2AMAPTNPSR1APOBEC3G | |
| Hydrochloric Acid SCHEMBL8645056 | 0.83 | MEN1 (0.65) | MEN1KMT2AMAPTNPSR1APOBEC3G | |
| SCHEMBL6003193 | 0.83 | MEN1 (0.65) | MEN1KMT2AMAPTNPSR1APOBEC3G | |
| SCHEMBL11347069 | 0.74 | MEN1 (0.54) | MEN1KMT2AMAPTNPSR1APOBEC3G | |
| Sulfuric Acid SCHEMBL8645100 | 0.73 | PDE7A (0.53) | MEN1KMT2AMAPTNPSR1APOBEC3G | |
| SCHEMBL2154630 | 0.73 | HAO1 (0.43) | APOBEC3GLMNA | |
| SCHEMBL1341376 | 0.73 | MEN1 (0.52) | MEN1KMT2AMAPTNPSR1APOBEC3G | |
| SCHEMBL3859717 | 0.73 | CYP3A4 (0.52) | MEN1KMT2AMAPTNPSR1APOBEC3G | |
| SCHEMBL11148598 | 0.73 | RHEB (0.46) | KMT2AMAPTNPSR1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859757-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | Farmak A.S. (CZ) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017325-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | FARMAK A.S. (CZ) | 1997-05-15 | — | — | WO | disclosed |
| US-3927093-A | 2-(O-aminophenylthio)benzyl alcohols | SQUIBB & SONS INC | 1975-12-16 | — | — | US | disclosed |