Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875025 | 0.85 | RECQL (0.52) | RECQLTSHRCYP3A4TDP1ATM | |
| SCHEMBL19529573 | 0.84 | RECQL (0.50) | RECQLTSHRCYP3A4TDP1ATM | |
| SCHEMBL7714717 | 0.81 | RECQL (0.47) | RECQLTSHRCYP3A4TDP1ATM | |
| SCHEMBL9572384 | 0.77 | RECQL (0.38) | RECQLTSHRCYP3A4TDP1ATM | |
| SCHEMBL19160284 | 0.75 | RECQL (0.62) | RECQLTSHRCYP3A4TDP1ATM | |
| SCHEMBL20343786 | 0.73 | RECQL (0.59) | RECQLTSHRCYP3A4TDP1ATM | |
| SCHEMBL260766 | 0.71 | RECQL (0.56) | RECQLTSHRCYP3A4TDP1ATM | |
| SCHEMBL28246238 | 0.70 | CYP3A4 (0.74) | RECQLTSHRCYP3A4TDP1ATM | |
| SCHEMBL13453089 | 0.70 | RECQL (0.55) | RECQLTSHRCYP3A4TDP1ATM | |
| SCHEMBL13741975 | 0.70 | RECQL (0.55) | RECQLTSHRCYP3A4TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574655-B1 | Lubricating compositions containing aromatic amine derivatives of 2,5-dimercapto-1,3,4-thiadiazoles | VANDERBILT CO R T (US) | 1998-04-08 | — | — | EP | disclosed |
| EP-0601266-B1 | Aromatic amine derivatives of 2,5-dimercapto-1,3,4-thiadiazoles | VANDERBILT CO R T (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5391756-A | Antiwear and antioxidant oil additives for lubricants | R. T. VANDERBILT COMPANY, INC. (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0601266-A1 | Aromatic amine derivatives of 2,5-dimercapto-1,3,4-thiadiazoles | R.T. VANDERBILT COMPANY, Inc. (US) | 1994-06-15 | — | — | EP | disclosed |
| EP-0574655-A1 | Lubricating compositions containing aromatic amine derivatives of 2,5-dimercapto-1,3,4-thiadiazoles | R.T. VANDERBILT COMPANY, Inc. (US) | 1993-12-22 | — | — | EP | disclosed |