Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 12/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 1.00 |
| ▸ | TACR1 | P25103 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31061390 | 1.00 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3TACR1 | |
| SCHEMBL6171525 | 0.85 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5448643 | 0.84 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3TACR1 | |
| SCHEMBL11505135 | 0.82 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11504855 | 0.81 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3TACR1 | |
| Hydrochloric Acid SCHEMBL11504975 | 0.81 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11504505 | 0.80 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11505429 | 0.80 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3TACR1 | |
| SCHEMBL11505065 | 0.79 | SLC6A4 (0.65) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11505294 | 0.79 | SLC6A4 (0.65) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854249-A | Opioid diarylmethylpiperazines and piperidines | DELTA PHARMACEUTICALS, INC. (US) | 1998-12-29 | — | — | US | disclosed |
| US-5681830-A | DIARYLMETHYL PIPERAZINE COMPOUNDS HAVING UTILITY IN MEDICAL THERAPY AS RECEPTOR-BINDING SPECIES | DELTA PHARMACEUTICALS, INC. (US) | 1997-10-28 | — | — | US | disclosed |
| US-4162316-A | ANALGESICS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1979-07-24 | — | — | US | disclosed |
| US-4080453-A | ANALGESICS, ANTITUSSIVE | DAINIPPON PHARMACEUTICAL CO., LTD. (JA) | 1978-03-21 | — | — | US | disclosed |