Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 4/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15750406 | 1.00 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8532508 | 1.00 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8531914 | 0.92 | HDAC3 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8531915 | 0.92 | HDAC3 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15750407 | 0.92 | HDAC3 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8531931 | 0.86 | SOAT1 (0.57) | SOAT1EPHX2ALDH1A1MAPTHPGD | |
| SCHEMBL8532602 | 0.86 | HPGD (0.54) | SOAT1EPHX2ALDH1A1MAPTHPGD | |
| SCHEMBL8532600 | 0.86 | HPGD (0.54) | SOAT1EPHX2ALDH1A1MAPTHPGD | |
| SCHEMBL8531933 | 0.86 | SOAT1 (0.57) | SOAT1EPHX2ALDH1A1MAPTHPGD | |
| SCHEMBL8537159 | 0.83 | SOAT1 (0.83) | SOAT1EPHX2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801178-A | ACAT INHIBITOR, ARTERIOSCLEROSIS | NIPPON SHOJI KAISH LTD. (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0726247-B1 | Aniline derivatives having a polyunsaturated fatty acid residue and use thereof | NIPPON SHOJI KAISHA LTD (JP) | 1998-07-08 | — | — | EP | disclosed |
| EP-0726247-A1 | Aniline derivatives having a polyunsaturated fatty acid residue and use thereof | NIPPON SHOJI KAISHA, LIMITED (JP) | 1996-08-14 | — | — | EP | disclosed |