Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.43 |
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530212 | 0.92 | SLC1A2 (0.42) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| SCHEMBL8533271 | 0.89 | SLC1A2 (0.40) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| Hydrochloric Acid SCHEMBL6703583 | 0.85 | GRM8 (0.41) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| SCHEMBL5690924 | 0.85 | SLC1A2 (0.46) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| SCHEMBL8354778 | 0.81 | SLC1A2 (0.43) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| Hydrochloric Acid SCHEMBL6702822 | 0.81 | SLC1A2 (0.38) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| SCHEMBL8358720 | 0.77 | SLC1A2 (0.44) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| SCHEMBL8354226 | 0.77 | SLC1A2 (0.44) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| SCHEMBL7124212 | 0.74 | SLC1A2 (0.50) | SLC1A2SLC1A1GRM8GRM6GRM2 | |
| SCHEMBL4810978 | 0.74 | SLC1A2 (0.50) | SLC1A2SLC1A1GRM8GRM6GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696577-B1 | Synthetic excitatory amino acids | LILLY CO ELI (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1996005175-A1 | SYNTHETIC EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 1996-02-22 | — | — | WO | disclosed |
| EP-0696577-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |