Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | KIF11 | P52732 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12435446 | 0.89 | P2RX1 (0.57) | MAPTMEN1KMT2ALMNAKIF11 | |
| SCHEMBL10308069 | 0.85 | ABCG2 (0.54) | MAPTMEN1KMT2ATRPV1NPSR1 | |
| SCHEMBL12694410 | 0.84 | MEN1 (0.63) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL12586249 | 0.83 | P2RX1 (0.49) | MAPTMEN1KMT2ALMNAKIF11 | |
| SCHEMBL12435451 | 0.83 | SLC13A3 (0.52) | MAPTMEN1KMT2ALMNAKIF11 | |
| SCHEMBL12435452 | 0.83 | P2RX1 (0.49) | MAPTMEN1KMT2ALMNAKIF11 | |
| SCHEMBL8095636 | 0.83 | MAPK14 (0.69) | MAPTMEN1KMT2ALMNAKIF11 | |
| SCHEMBL16907464 | 0.83 | MAPT (0.66) | MAPTMEN1KMT2ALMNATRPV1 | |
| SCHEMBL22225457 | 0.82 | TRPV1 (0.63) | MAPTMEN1KMT2ALMNAKIF11 | |
| SCHEMBL23447712 | 0.82 | MAPT (0.63) | MAPTMEN1KMT2ALMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |