Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29886728 | 0.83 | PTPN1 (0.61) | SMN1; SMN2KDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL4160389 | 0.83 | PTPN1 (0.61) | SMN1; SMN2KDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL10353860 | 0.80 | NPC1 (0.46) | SMN1; SMN2KDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL5872224 | 0.79 | HDAC1 (0.60) | SMN1; SMN2KDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL1941975 | 0.78 | TDP1 (0.57) | SMN1; SMN2KDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL4108418 | 0.77 | SMN1; SMN2 (0.73) | SMN1; SMN2KDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL11253655 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL3527398 | 0.77 | SMN1; SMN2 (0.72) | SMN1; SMN2KDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL4587220 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL29435967 | 0.77 | SMN1; SMN2 (0.72) | SMN1; SMN2KDM4EHPGDALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216522-A | Therapeutic agent for diabetes | JAPAN TOBACCO INC (JP) | 1999-05-12 | — | — | CN | disclosed |
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5776365-A | COMPOUNDS WITH OPTICAL ACTIVITY AND SWITCHES FOR CONTRAST | MITSUI CHEMICALS, INC. (JP) | 1998-07-07 | — | — | US | disclosed |
| US-5725798-A | CARBOXYLIC ESTERS FOR ELECTRICAL APPARATUS, SWITCHES AND CONTRAST | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-10 | — | — | US | disclosed |