Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SPOP | O43791 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010087 | 1.00 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL27938962 | 1.00 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL10820995 | 1.00 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL10840113 | 1.00 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| Acetic Acid SCHEMBL10821202 | 0.98 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| Acetic Acid SCHEMBL11098482 | 0.98 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| Methylene Chloride SCHEMBL11134298 | 0.98 | PLCG1 (0.65) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| Acetic Acid SCHEMBL10821201 | 0.98 | PLCG1 (0.68) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| Propionic Acid SCHEMBL11138117 | 0.96 | PLCG1 (0.66) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 | |
| SCHEMBL11731807 | 0.92 | PLCG1 (0.62) | PLCG1L3MBTL1CTDSP1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824801-A | REACTING CORRESPONDING EXOMETHYLENE COMPOUND WITH OZONE, DECOMPOSITION WITHOUT REDUCING AGENT | LUPIN LABORATORIES LTD. (IN) | 1998-10-20 | — | — | US | disclosed |
| US-5750683-A | CHEMICAL INTERMEDIATES FOR BIOSYNTHESIS OF CAPHALOISPORIN ANTIBIOTICS | LUPIN LABORATORIES, LTD. (IN) | 1998-05-12 | — | — | US | disclosed |
| US-4604386-A | CONTROL OF GRAMPOSITIVE BACTERIA | ELI LILLY AND COMPANY (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0168222-A2 | 3-(Alkynylalkyloxy) Cephalosporins | ELI LILLY AND COMPANY (US) | 1986-01-15 | — | — | EP | disclosed |
| US-4518531-A | Allylic chlorination process and compounds prepared thereby | ELI LILLY AND COMPANY (US) | 1985-05-21 | — | — | US | disclosed |
| US-4473567-A | Substituted-imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid | SHIONOGI & CO., LTD. (JP) | 1984-09-25 | — | — | US | disclosed |
| US-4440683-A | Cyclization to form cephem ring and azetidinone intermediates therefor | SHIONOGI & CO., LTD. (JP) | 1984-04-03 | — | — | US | disclosed |
| EP-0019401-B1 | PROCESS FOR PREPARING ENAMINE DERIVATIVES, COMPOUNDS SO PRODUCED AND PROCESS FOR PREPARING A 3-HYDROXY-CEPHALOSPORIN | Lilly Industries Limited (GB) | 1984-03-21 | — | — | EP | disclosed |
| US-4430268-A | Allylic chlorination process | ELI LILLY AND COMPANY (US) | 1984-02-07 | — | — | US | disclosed |
| EP-0014567-B1 | PROCESSES FOR PREPARATION OF BETA-LACTAM COMPOUNDS | ELI LILLY AND COMPANY (US) | 1984-01-18 | — | — | EP | disclosed |
| US-4160085-A | Cyclization to form cephem ring and intermediates therefor | SHIONOGI & CO., LTD. (JP) | 1979-07-03 | — | — | US | disclosed |
| US-4133808-A | 4-(Formylthio)azetidinones and ozonization process therefor | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4115643-A | Process for 3-chloro cephalosporins | ELI LILLY AND COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4079181-A | INTERMEDIATES FOR 3-HYDROXY-3-CEPHEM COMPOUNDS | SHIONOGI & CO., LTD. (JA) | 1978-03-14 | — | — | US | disclosed |
| US-4065618-A | Process for 3-H-3-cephem esters | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4065621-A | Process for 3-alkyl and 3-phenyl cephalosporins | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4060688-A | Cephalosporin intermediates | ELI LILLY AND COMPANY (US) | 1977-11-29 | — | — | US | disclosed |
| US-4048157-A | 4(Formylthio)-azetidin-2-ones and ozonization process therefor | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4044002-A | ACYL BROMIDES AND A BROMINE SCAVENGER | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4013651-A | 3-SUBSTITUTED AMINO-CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1977-03-22 | — | — | US | disclosed |