Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855558 | 0.96 | TLR7 (0.74) | TLR7 | |
| SCHEMBL2844424 | 0.94 | TLR7 (0.73) | TLR7 | |
| SCHEMBL30036407 | 0.94 | TLR7 (0.73) | TLR7 | |
| SCHEMBL854957 | 0.89 | TLR7 (0.74) | TLR7 | |
| SCHEMBL29352884 | 0.89 | TLR7 (0.74) | TLR7 | |
| SCHEMBL853435 | 0.87 | TLR7 (0.74) | TLR7 | |
| SCHEMBL30036415 | 0.86 | TLR7 (0.75) | TLR7 | |
| SCHEMBL30036392 | 0.86 | TLR7 (0.75) | TLR7 | |
| SCHEMBL20212217 | 0.86 | TLR7 (0.75) | TLR7 | |
| SCHEMBL853929 | 0.85 | TLR7 (0.66) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432768-A1 | NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND FURTHER DISEASES | AstraZeneca AB (SE) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133885-A1 | NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND FURTHER DISEASES | ASTRAZENECA AB (SE) | 2010-11-25 | — | — | WO | disclosed |