Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 4/20 | 0.62 |
| ▸ | WNT3A | P56704 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089541 | 0.92 | CTNNB1 (0.70) | CTNNB1WNT3AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL29062364 | 0.92 | CTNNB1 (0.70) | CTNNB1WNT3AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL4937541 | 0.85 | CTNNB1 (0.62) | CTNNB1WNT3AHPGDSMN1; SMN2PARP1 | |
| SCHEMBL29698182 | 0.85 | CTNNB1 (0.62) | CTNNB1WNT3AHPGDSMN1; SMN2PARP1 | |
| SCHEMBL10790435 | 0.84 | CTNNB1 (0.65) | CTNNB1WNT3AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL2027904 | 0.83 | CTNNB1 (0.59) | CTNNB1WNT3AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL3039881 | 0.83 | HDAC8 (0.56) | CTNNB1WNT3AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL10788703 | 0.83 | CTNNB1 (0.64) | CTNNB1WNT3AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL15980082 | 0.82 | CTNNB1 (0.63) | CTNNB1WNT3AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL11382023 | 0.81 | CTNNB1 (0.58) | CTNNB1WNT3AHPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |