Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536717 | 0.94 | MCHR1 (0.46) | PTPN11MCHR1PLK1TAOK3FAAH | |
| SCHEMBL8585474 | 0.86 | MCHR1 (0.45) | MCHR1PLK1FAAH | |
| SCHEMBL8533724 | 0.86 | TAOK3 (0.44) | TAOK3THRAPPARDTAOK1TP53 | |
| SCHEMBL8531873 | 0.86 | FFAR1 (0.46) | MCHR1THRATP53TSHR | |
| SCHEMBL8537387 | 0.86 | FFAR1 (0.46) | MCHR1THRATP53TSHR | |
| SCHEMBL8536356 | 0.84 | NPC1 (0.45) | MCHR1THRATP53TSHR | |
| SCHEMBL8535797 | 0.80 | MCHR1 (0.44) | MCHR1TAOK3THRATP53TSHR | |
| SCHEMBL8533378 | 0.80 | PTPN11 (0.46) | PTPN11MCHR1PLK1TAOK3TAOK1 | |
| SCHEMBL8532517 | 0.79 | MCHR1 (0.41) | PTPN11MCHR1PLK1TAOK3TP53 | |
| SCHEMBL8536472 | 0.79 | NPC1 (0.50) | MCHR1TAOK3TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776365-A | COMPOUNDS WITH OPTICAL ACTIVITY AND SWITCHES FOR CONTRAST | MITSUI CHEMICALS, INC. (JP) | 1998-07-07 | — | — | US | disclosed |
| US-5725798-A | CARBOXYLIC ESTERS FOR ELECTRICAL APPARATUS, SWITCHES AND CONTRAST | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-10 | — | — | US | disclosed |