Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CCL2 | P13500 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694747 | 0.79 | BRD4 (0.55) | BRD4CCL2ATMHTR2AALDH1A1 | |
| SCHEMBL7570833 | 0.79 | BRD4 (0.42) | BRD4CCL2ATMHTR2AALDH1A1 | |
| SCHEMBL14156129 | 0.74 | ATM (0.47) | BRD4CCL2ATMALDH1A1MAPT | |
| SCHEMBL27682027 | 0.72 | BRD4 (0.40) | BRD4CCL2ATMHTR2AALDH1A1 | |
| Bromide SCHEMBL10686124 | 0.72 | BRD4 (0.44) | BRD4CCL2ATMHTR2AALDH1A1 | |
| SCHEMBL10688105 | 0.71 | BRD4 (0.46) | BRD4CCL2ATMHTR2AALDH1A1 | |
| SCHEMBL11155913 | 0.69 | BRD4 (0.49) | BRD4CCL2ATMHTR2AALDH1A1 | |
| SCHEMBL16144149 | 0.69 | KDM4E (0.37) | HTR2AALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL28177977 | 0.69 | BRD4 (0.41) | BRD4CCL2ATMHTR2AALDH1A1 | |
| SCHEMBL5532790 | 0.68 | PRCP (0.44) | BRD4CCL2HTR2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |