Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 16/20 | 0.48 |
| ▸ | FNTB | P49356 | 16/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 15/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095893 | 1.00 | FNTA (0.48) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL446562 | 0.94 | FNTA (0.54) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8444323 | 0.93 | KCNH2 (0.49) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8097462 | 0.93 | KCNH2 (0.49) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8426008 | 0.91 | FNTA (0.49) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8095566 | 0.91 | FNTA (0.49) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8433745 | 0.90 | FNTA (0.51) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8095475 | 0.90 | FNTA (0.51) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8088419 | 0.90 | FNTA (0.47) | FNTAFNTBPGGT1BKCNH2GPBAR1 | |
| SCHEMBL8436084 | 0.90 | FNTA (0.47) | FNTAFNTBPGGT1BKCNH2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817678-A | IMIDAZOLE-CONTAINING PIPERIDINE DERIVATIVES, PEPTIDEMIMETIC | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | disclosed |