SCHEMBL8535286

SCHEMBL8535286

CN(C)Cc1ccc2ccccc2c1O

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.59
MAPT P10636 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
NPY1R P25929 1/20 0.53
MAPK1 P28482 1/20 0.53
NPY2R P49146 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11596899 0.82 CYP1A2 (0.49)
SCHEMBL31332266 0.82 HTR2A (0.50)
SCHEMBL9138641 0.79 KDM4E (0.66) KDM4EMAPTTDP1ALDH1A1LMNA
Hydrochloric Acid SCHEMBL146079 0.79 CYP2D6 (0.74) KDM4EMAPTTDP1ALDH1A1LMNA
SCHEMBL29886792 0.79
SCHEMBL2167788 0.79
Hydrochloric Acid SCHEMBL2278072 0.79 CYP2D6 (0.74) KDM4EMAPTTDP1ALDH1A1LMNA
SCHEMBL130289 0.78 PTPN22 (0.58)
SCHEMBL29354413 0.78
SCHEMBL6010301 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114671771-A Preparation method of amino naphthol 岳阳中展科技有限公司 2022-06-28 CN disclosed
EP-0630642-B1 Naphthol couplers BRISTOL MYERS SQUIBB CO (US) 1998-08-12 EP disclosed
EP-0371508-A1 Phenoxy and phenylthio, amino substituted benzocycloalkane derivatives in the treatment and prevention of drug-resistant protozoal infections MERRELL DOW PHARMACEUTICALS INC. (US) 1990-06-06 EP disclosed