Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.57 |
| ▸ | FNTA | P49354 | 13/20 | 0.49 |
| ▸ | FNTB | P49356 | 13/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 13/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531142 | 0.80 | CYP11B1 (0.59) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8097403 | 0.79 | CYP11B1 (0.49) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8534856 | 0.79 | CYP11B1 (0.49) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8534308 | 0.79 | CYP11B1 (0.58) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8534304 | 0.78 | CYP11B1 (0.49) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7083862 | 0.78 | CYP11B1 (0.56) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL6776413 | 0.73 | CYP11B1 (0.85) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL1658172 | 0.73 | CYP11B1 (0.55) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8191731 | 0.73 | CYP11B1 (0.73) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7830288 | 0.73 | CYP11B1 (0.58) | CYP11B1CYP11B2FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817678-A | IMIDAZOLE-CONTAINING PIPERIDINE DERIVATIVES, PEPTIDEMIMETIC | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | disclosed |