Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.33 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539842 | 0.82 | HTR2C (0.47) | HTR2CPTGS1PTGS2XDHHIF1A | |
| SCHEMBL8534981 | 0.78 | CA12 (0.40) | PTGS1PTGS2XDHCA12CA9 | |
| SCHEMBL8535288 | 0.76 | TLR3 (0.46) | PTGS1PTGS2XDHCA12CA9 | |
| SCHEMBL28738550 | 0.74 | PTGS1 (0.35) | NPSR1HTR2CPTGS1PTGS2XDH | |
| SCHEMBL482227 | 0.74 | NPSR1 (0.49) | NPSR1HTR2CPTGS1PTGS2XDH | |
| SCHEMBL6981088 | 0.72 | NPSR1 (0.43) | NPSR1HTR2CPTGS1PTGS2XDH | |
| SCHEMBL16695056 | 0.66 | HIF1A (0.40) | NPSR1HTR2CPTGS1PTGS2XDH | |
| SCHEMBL31543816 | 0.66 | HTR2C (0.60) | NPSR1HTR2CCA12CA2CA9 | |
| SCHEMBL20270447 | 0.65 | HTR2C (0.81) | NPSR1HTR2CCA12CA2CA9 | |
| SCHEMBL31235894 | 0.65 | HTR2C (0.81) | NPSR1HTR2CCA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |