Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 5/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531854 | 0.93 | CYP19A1 (0.60) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL8536549 | 0.92 | CYP19A1 (0.58) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL7166102 | 0.91 | CYP19A1 (0.57) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL9448254 | 0.86 | CYP19A1 (0.55) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL8531749 | 0.83 | CYP19A1 (0.52) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL9343214 | 0.82 | CYP19A1 (0.61) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL7226512 | 0.82 | KDM4E (0.53) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL15700133 | 0.81 | CYP19A1 (0.67) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL8673224 | 0.81 | CYP19A1 (0.60) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL8673226 | 0.81 | CYP19A1 (0.60) | CYP19A1KDM4ELMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847159-A | 1- ω-(3,4-dihydro-2-naphthalenyl)alkyl!-cyclic amine derivatives, process for preparing the same, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| EP-0825180-A1 | 1-OMEGA-(3,4-DIHYDRO-2-NAPHTHALENYL)ALKYL] CYCLIC AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |