SCHEMBL8536244

SCHEMBL8536244

COc1cc([N+](=O)[O-])ccc1NN

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.66
PKM P14618 1/20 0.66
TDP1 Q9NUW8 1/20 0.58
LMNA P02545 3/20 0.58
KMT2A Q03164 3/20 0.58
ALDH1A1 P00352 5/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
GAA P10253 2/20 0.57
GLA P06280 1/20 0.57
EPHX1 P07099 1/20 0.57
MAPT P10636 2/20 0.56
RECQL P46063 1/20 0.56
DUSP3 P51452 1/20 0.56
PTPN5 P54829 1/20 0.56
PTPN11 Q06124 1/20 0.56
KCNMA1 Q12791 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20984252 0.98 HTT (0.64) HTTPKMTDP1LMNAKMT2A
Bromide SCHEMBL20984908 0.98 HTT (0.64) HTTPKMTDP1LMNAKMT2A
Nitric Acid SCHEMBL20984640 0.95 HTT (0.65) HTTPKMTDP1LMNAKMT2A
Phosphoric Acid SCHEMBL20984300 0.93 HTT (0.62) HTTPKMTDP1LMNAKMT2A
Sulfuric Acid SCHEMBL20984198 0.93 HTT (0.62) HTTPKMTDP1LMNAKMT2A
Oxalic Acid SCHEMBL20984610 0.93 HTT (0.66) HTTPKMLMNAKMT2AALDH1A1
SCHEMBL20302624 0.87 SMN1; SMN2 (0.68) HTTTDP1LMNAKMT2AALDH1A1
SCHEMBL30311318 0.87 SMN1; SMN2 (0.68) HTTTDP1LMNAKMT2AALDH1A1
Hydrochloric Acid SCHEMBL20984568 0.85 SMN1; SMN2 (0.66) HTTTDP1LMNAKMT2AALDH1A1
Bromide SCHEMBL20984828 0.85 SMN1; SMN2 (0.66) HTTTDP1LMNAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0797789-B1 NOVEL DIHYDRAZIDES AS DOT-PROMOTING AGENTS IN PHOTOGRAPHIC IMAGE SYSTEMS INT PAPER CO (US) 1998-11-25 EP disclosed
US-4030925-A Photographic compositions and elements including internal latent image silver halide grains and acylhydrazinophenylthiourea nucleating agents therefor EASTMAN KODAK COMPANY (US) 1977-06-21 US disclosed
US-4031127-A Acyl hydrazino thiourea derivatives as photographic nucleating agents EASTMAN KODAK COMPANY (US) 1977-06-21 US disclosed