Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 17/20 | 0.48 |
| ▸ | CA2 | P00918 | 16/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 8/20 | 0.32 |
| ▸ | CA7 | P43166 | 4/20 | 0.31 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4400378 | 0.81 | CA1 (0.40) | CA1CA2CA12CA14CA7 | |
| SCHEMBL13395823 | 0.73 | CA1 (0.35) | CA1CA2CA12CA14 | |
| SCHEMBL12725413 | 0.71 | CA1 (0.33) | CA1CA2CA12CA14 | |
| SCHEMBL8539785 | 0.69 | CA1 (0.44) | CA1CA2CA12CA14CA9 | |
| SCHEMBL41726 | 0.69 | — | — | |
| SCHEMBL1098560 | 0.67 | — | — | |
| SCHEMBL15368928 | 0.67 | CA1 (0.35) | CA1CA2CA12CA14 | |
| SCHEMBL10519458 | 0.67 | CA1 (0.33) | CA1CA2CA12CA14 | |
| Sulfamide SCHEMBL9647921 | 0.66 | — | — | |
| Sulfamide SCHEMBL10457261 | 0.66 | CA1 (0.55) | CA1CA2CA12CA14CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467251-B1 | Process for the preparation of N-alkylsulfonylaminosulfonyl ureas | HOECHST SCHERING AGREVO GMBH (DE) | 1998-06-03 | — | — | EP | disclosed |
| US-5155222-A | PROCESS FOR THE PREPARATION OF N-ALKYLSULFONYLAMINOSULFONYLUREAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-13 | — | — | US | disclosed |
| EP-0467251-A2 | Process for the preparation of N-alkylsulfonylaminosulfonyl ureas | Hoechst Schering AgrEvo GmbH (DE) | 1992-01-22 | — | — | EP | disclosed |