Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049725 | 0.85 | TSHR (0.50) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL11056346 | 0.85 | TSHR (0.55) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL14211584 | 0.84 | TSHR (0.72) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL7643867 | 0.82 | TSHR (0.68) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL5579130 | 0.82 | TSHR (0.75) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL3234929 | 0.81 | TSHR (0.55) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL23529791 | 0.79 | CYP1A2 (0.59) | TSHRALDH1A1TDP1CYP1A2MAPK1 | |
| SCHEMBL29804161 | 0.79 | CYP1A2 (0.59) | TSHRALDH1A1TDP1CYP1A2MAPK1 | |
| SCHEMBL2519558 | 0.79 | TSHR (0.55) | TSHRALDH1A1TDP1CYP1A2GPR35 | |
| SCHEMBL9194645 | 0.78 | TSHR (0.61) | TSHRALDH1A1TDP1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591059-B1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | OREAL (FR) | 1998-04-15 | — | — | EP | disclosed |
| US-5534036-A | Keratinous fiber dyeing methods and compositions which contain sulfated methaphenylenediamine couplers in combination with oxidation dye precursors | L'OREAL (FR) | 1996-07-09 | — | — | US | disclosed |
| EP-0591059-A1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | L'OREAL (FR) | 1994-04-06 | — | — | EP | disclosed |
| EP-0057871-B1 | PROCESS FOR THE PREPARATION OF OPTIONALLY P-CHLORO-SUBSTITUTED 2,6-DIAMINO TOLUENE | BAYER AG (DE) | 1984-10-03 | — | — | EP | disclosed |
| US-4426538-A | Process for the preparation of optionally p-chlorine-substituted 2,6-diaminotoluene | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-17 | — | — | US | disclosed |
| EP-0057871-A2 | Process for the preparation of optionally p-chloro-substituted 2,6-diamino toluene | BAYER AG (DE) | 1982-08-18 | — | — | EP | disclosed |