Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 12/20 | 0.35 |
| ▸ | TK1 | P04183 | 4/20 | 0.34 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536368 | 1.00 | TK2 (0.35) | TK2TK1RNASE1 | |
| SCHEMBL8535800 | 0.91 | TK2 (0.36) | TK2TK1 | |
| SCHEMBL8532612 | 0.91 | TK2 (0.36) | TK2TK1 | |
| SCHEMBL8537057 | 0.91 | TK2 (0.32) | TK2TK1 | |
| SCHEMBL8537059 | 0.91 | TK2 (0.32) | TK2TK1 | |
| SCHEMBL9197110 | 0.88 | TK2 (0.36) | TK2TK1 | |
| SCHEMBL8533524 | 0.88 | TK2 (0.36) | TK2TK1 | |
| SCHEMBL8535383 | 0.78 | TK2 (0.36) | TK2TK1 | |
| SCHEMBL8535388 | 0.78 | TK2 (0.36) | TK2TK1 | |
| SCHEMBL8536619 | 0.77 | TK2 (0.34) | TK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750343-A | Methods of detecting nucleic acids with nucleotide probes containing 4'-substituted nucleotides and kits therefor | SYNTEX INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5446137-A | Substituent selected from linking group containing modifiers such as biotin, reactive groups, nucleic acids, catalysts, DNA intercalators, minor groove binders, clevage agents, and detectable labels | SYNTEX (U.S.A.) INC. (US) | 1995-08-29 | — | — | US | disclosed |