Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536405 | 1.00 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3LMNATSHR | |
| SCHEMBL7215838 | 0.93 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3LMNAKDM4E | |
| SCHEMBL521277 | 0.84 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1023136 | 0.78 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1023137 | 0.78 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6492534 | 0.78 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL1022136 | 0.76 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL12723073 | 0.76 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11988479 | 0.75 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL1122233 | 0.74 | SLC6A4 (0.64) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819126-A1 | BIPHENYLAMIDE DERIVATIVES AS 5HT 1D? ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031508-A1 | BIPHENYLAMIDE DERIVATIVES AS 5HT1D ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-10-10 | — | — | WO | disclosed |