SCHEMBL8536706

SCHEMBL8536706

CCCCCCCCCCOc1ccc(-c2ccc(C(=O)Oc3ccc4c(c3)CCC(C(=O)O)C4)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.54
RARB P10826 4/20 0.51
NPC1 O15118 2/20 0.47
LMNA P02545 2/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
FFAR1 O14842 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
S1PR5 Q9H228 5/20 0.45
PLA2G4B P0C869 1/20 0.45
S1PR1 P21453 5/20 0.44
S1PR3 Q99500 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8536045 1.00 MCHR1 (0.54) MCHR1RARBNPC1LMNANFKB1
SCHEMBL8531556 1.00 MCHR1 (0.54) MCHR1RARBNPC1LMNANFKB1
SCHEMBL8533685 1.00 MCHR1 (0.54) MCHR1RARBNPC1LMNANFKB1
SCHEMBL8531861 1.00 MCHR1 (0.54) MCHR1RARBNPC1LMNANFKB1
SCHEMBL8533608 1.00 MCHR1 (0.54) MCHR1RARBNPC1LMNANFKB1
SCHEMBL8536472 0.97 NPC1 (0.50) MCHR1RARBNPC1LMNANFKB1
SCHEMBL8536356 0.90 NPC1 (0.45) MCHR1NPC1LMNANFKB1NFKB2
SCHEMBL8532711 0.90 MCHR1 (0.53) MCHR1RARBSMN1; SMN2FFAR1S1PR5
SCHEMBL8537443 0.90 MCHR1 (0.53) MCHR1RARBSMN1; SMN2FFAR1S1PR5
SCHEMBL8531873 0.90 FFAR1 (0.46) MCHR1NPC1LMNANFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8157423-A None JP disclosed
US-5776365-A COMPOUNDS WITH OPTICAL ACTIVITY AND SWITCHES FOR CONTRAST MITSUI CHEMICALS, INC. (JP) 1998-07-07 US disclosed
US-5725798-A CARBOXYLIC ESTERS FOR ELECTRICAL APPARATUS, SWITCHES AND CONTRAST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-10 US disclosed
JP-H08157423-A LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL ELEMENT MITSUI PETROCHEM IND LTD 1996-06-18 JP disclosed