Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7062958 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL28079816 | 1.00 | — | — | |
| Bicarbonate SCHEMBL20162491 | 0.94 | — | — | |
| Bicarbonate SCHEMBL168136 | 0.93 | — | — | |
| Bicarbonate SCHEMBL537207 | 0.93 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL4437082 | 0.93 | — | — | |
| Bicarbonate SCHEMBL166675 | 0.93 | — | — | |
| Bicarbonate SCHEMBL22117427 | 0.93 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL136536 | 0.93 | — | — | |
| Bicarbonate SCHEMBL4359129 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111790418-B | Calcium-titanium composite material and preparation method and application thereof | 国家纳米科学中心 | 2023-05-26 | — | — | CN | claimed |
| CN-109181079-B | Preparation method and application of calcium carbonate/titanium dioxide composite material | 河北化工医药职业技术学院 | 2021-08-13 | — | — | CN | claimed |
| CN-112940395-A | Fragrant anti-aging PP plastic and fragrant anti-aging PP clothes hanger | 晋江市春水衣架有限公司 | 2021-06-11 | — | — | CN | claimed |
| CN-111790418-A | Calcium-titanium composite material and preparation method and application thereof | 国家纳米科学中心 | 2020-10-20 | — | — | CN | claimed |
| CN-109181079-A | A kind of preparation method and applications of calcium carbonate/composite titania material | 河北化工医药职业技术学院 | 2019-01-11 | — | — | CN | claimed |
| CN-104031421-B | A kind of preparation method with the nano-calcium carbonate/titanium dioxide composite powder of nucleocapsid structure | JILIN UNIVERSITY (CN) | 2016-04-13 | — | — | CN | claimed |
| CN-104031421-A | Preparation method of nano calcium carbonate/titanium dioxide composite powder with core-shell structure | UNIV JILIN | 2014-09-10 | — | — | CN | claimed |
| CN-117342595-A | Preparation method of high-whiteness acid-resistant core-shell structure calcium carbonate | 广西华纳新材料股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-111790418-B | Calcium-titanium composite material and preparation method and application thereof | 国家纳米科学中心 | 2023-05-26 | — | — | CN | disclosed |
| CN-113956059-B | High-strength suspension insulator for high-voltage transmission line | 江西凯佳电瓷电器有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-113979733-B | Manufacturing and processing technology of electric power stay insulator | 江西凯佳电瓷电器有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-113480845-B | Regenerated PA plastic particle prepared from waste cloth and method thereof | 江西省铭新科技有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-110980787-B | Preparation method of calcium carbonate-calcium sulfate nano composite chain material | 广西华纳新材料股份有限公司 | 2022-07-19 | — | — | CN | disclosed |
| EP-0326410-B1 | WATERPROOF LAMINATED PAPER AND PRODUCTION PROCESS THEREOF | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0326410-A2 | Waterproof laminated paper and production process thereof | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| US-4772653-A | Stain resistant cookware from blends comprising an interpolymer of an unsaturated dicarboxylic acid compound | AMOCO CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| US-4518681-A | FILM, BLEND OF STYRENE POLYMERS AND POLYETHYLENE, TITANIUM DIOXIDEFILLER | THE DOW CHEMICAL COMPANY (US) | 1985-05-21 | — | — | US | disclosed |
| US-4460647-A | TITANIUM DIOXIDE LIGHT SCATTERING PIGMENT | CELANESE CORPORATION (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0068433-A1 | Process for the manufacture of synthetic paper and the product thereof | THE DOW CHEMICAL COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |
| US-4115283-A | POLY(ARYLENE SULFIDE), LUBRICANTS, FILLERS | PHILLIPS PETROLEUM COMPANY (US) | 1978-09-19 | — | — | US | disclosed |