Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 10/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.36 |
| ▸ | TSHR | P16473 | 8/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10380882 | 1.00 | CYP3A4 (0.36) | CYP3A4CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL8536926 | 0.80 | — | — | |
| SCHEMBL8544220 | 0.80 | — | — | |
| SCHEMBL8538898 | 0.80 | — | — | |
| SCHEMBL8536976 | 0.77 | — | — | |
| SCHEMBL8536971 | 0.74 | — | — | |
| SCHEMBL8538649 | 0.74 | — | — | |
| SCHEMBL9310557 | 0.74 | — | — | |
| SCHEMBL9310906 | 0.74 | — | — | |
| SCHEMBL9309452 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358154-B1 | Novel cyclobutane derivative and process for producing same | NIPPON KAYAKU KK (JP) | 1998-12-02 | — | — | EP | disclosed |
| EP-0358154-A2 | Novel cyclobutane derivative and process for producing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1990-03-14 | — | — | EP | disclosed |