Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024498 | 0.89 | TACR1 (0.70) | TACR1 | |
| SCHEMBL9024496 | 0.89 | TACR1 (0.70) | TACR1 | |
| SCHEMBL8539698 | 0.87 | TACR1 (0.62) | TACR1 | |
| SCHEMBL9194148 | 0.85 | TACR1 (0.77) | TACR1 | |
| SCHEMBL9544240 | 0.85 | TACR1 (0.77) | TACR1 | |
| SCHEMBL8539701 | 0.84 | TACR1 (0.73) | TACR1 | |
| Hydrochloric Acid SCHEMBL9076697 | 0.84 | TACR1 (0.75) | TACR1 | |
| Hydrochloric Acid SCHEMBL9076701 | 0.84 | TACR1 (0.75) | TACR1 | |
| SCHEMBL8539538 | 0.84 | TACR1 (0.64) | TACR1 | |
| SCHEMBL8545494 | 0.83 | TACR1 (0.64) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652866-B1 | AZACYCLIC COMPOUNDS | MERCK SHARP & DOHME (GB) | 1998-11-25 | — | — | EP | claimed |
| EP-0652866-A1 | AZACYCLIC COMPOUNDS | MERCK SHARP & DOHME LTD. (GB) | 1995-05-17 | — | — | EP | claimed |
| EP-0652866-B1 | AZACYCLIC COMPOUNDS | MERCK SHARP & DOHME (GB) | 1998-11-25 | — | — | EP | disclosed |