Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | FAAH | O00519 | 2/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ADH1B | P00325 | 2/20 | 0.42 |
| ▸ | ADH1C | P00326 | 2/20 | 0.42 |
| ▸ | ADH1A | P07327 | 2/20 | 0.42 |
| ▸ | ADH4 | P08319 | 2/20 | 0.42 |
| ▸ | ADH7 | P40394 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265824 | 1.00 | TSHR (0.67) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL9263907 | 1.00 | TSHR (0.67) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL9265049 | 0.96 | TSHR (0.60) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL29109640 | 0.96 | TSHR (0.60) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL8423881 | 0.94 | TSHR (0.56) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL11687766 | 0.92 | TSHR (0.54) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL9257092 | 0.92 | TSHR (0.54) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL22602593 | 0.91 | TSHR (0.73) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL1826406 | 0.89 | TSHR (0.50) | TSHRFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL8349861 | 0.89 | TSHR (0.50) | TSHRFAAHTRPV1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747066-A | PHOSPHATIDES, BILE ACID SALT OR DIHEXANOYLLECITHIN | HOFFMANN-LA ROCHE INC. (US) | 1998-05-05 | — | — | US | disclosed |