⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28203961 | 0.81 | TSHR (0.46) | — | |
| SCHEMBL3387966 | 0.80 | TSHR (0.50) | — | |
| SCHEMBL3392585 | 0.80 | TSHR (0.50) | — | |
| SCHEMBL2884218 | 0.78 | — | — | |
| SCHEMBL50343 | 0.78 | — | — | |
| SCHEMBL16305432 | 0.78 | — | — | |
| SCHEMBL27523170 | 0.77 | TSHR (0.38) | — | |
| SCHEMBL215694 | 0.76 | — | — | |
| SCHEMBL408993 | 0.76 | TSHR (0.46) | — | |
| SCHEMBL651808 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628558-B1 | Process for the synthesis of 9(2-hydroxyethoxy methyl) guanine | SOLAR CHEM SA (LU) | 1998-04-15 | — | — | EP | disclosed |
| US-5496945-A | Process for the synthesis of 9-(2-hydroxyethoxy methyl) guanine | SOLAR CHEMICAL S.A. (LU) | 1996-03-05 | — | — | US | disclosed |
| EP-0628558-A1 | Process for the synthesis of 9(2-hydroxyethoxy methyl) guanine | SOLAR CHEMICAL S.A. (LU) | 1994-12-14 | — | — | EP | disclosed |