Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.70 |
| ▸ | MEN1 | O00255 | 8/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5305524 | 1.00 | MAPT (0.70) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL4278062 | 1.00 | MAPT (0.70) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL28044369 | 1.00 | MAPT (0.70) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| Formaldehyde SCHEMBL27032562 | 0.96 | MAPT (0.66) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL11171730 | 0.94 | MAPT (0.64) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL11171727 | 0.94 | MAPT (0.64) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| Azobenzene SCHEMBL27907202 | 0.93 | MEN1 (0.64) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL3282776 | 0.89 | MEN1 (0.61) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL3282773 | 0.89 | MEN1 (0.61) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL9241290 | 0.87 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175971-A | Supermolecule bisazo benzene compound and preparation method thereof | UNIV ANHUI | 2015-12-23 | — | — | CN | disclosed |
| US-7544308-B2 | Dichroic dye and microencapsulated liquid crystal composition thereof | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2009-06-09 | — | — | US | disclosed |
| US-7544308-B2 | Dichroic dye and microencapsulated liquid crystal composition thereof | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2009-06-09 | — | — | US | disclosed |
| US-5782934-A | Process of dyeing with disazo dyes containing a fluorosulphonyl group and use thereof | ZENECA LIMITED (GB) | 1998-07-21 | — | — | US | disclosed |