Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543959 | 0.88 | CYP2C9 (0.43) | TSHRCYP3A4CYP2C9KDM4EKMT2A | |
| SCHEMBL8541237 | 0.86 | CYP2C19 (0.43) | TSHRCYP3A4PTGS1PTGS2CYP1A2 | |
| SCHEMBL8545725 | 0.75 | PTGS1 (0.48) | TSHRCYP3A4PTGS1PTGS2CYP1A2 | |
| SCHEMBL9266621 | 0.75 | CYP3A4 (0.46) | TSHRCYP3A4PTGS1PTGS2CYP1A2 | |
| SCHEMBL8543445 | 0.75 | CYP2C19 (0.45) | TSHRCYP1A2KDM4EKMT2AMEN1 | |
| SCHEMBL10346356 | 0.74 | SMN1; SMN2 (0.45) | TSHRCYP2C9KDM4EKMT2AMEN1 | |
| SCHEMBL9010118 | 0.72 | PTGS1 (0.55) | TSHRCYP3A4PTGS1PTGS2CYP1A2 | |
| SCHEMBL8544837 | 0.72 | CYP3A4 (0.52) | TSHRCYP3A4PTGS1PTGS2CYP1A2 | |
| SCHEMBL2059447 | 0.72 | TSHR (0.55) | TSHRCYP3A4PTGS1PTGS2CYP1A2 | |
| SCHEMBL8539212 | 0.71 | CYP3A4 (0.47) | TSHRCYP3A4PTGS1PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587499-B1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR (FR) | 1998-04-29 | — | — | EP | disclosed |
| US-5395834-A | Antiarthritic agents or cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1995-03-07 | — | — | US | disclosed |
| US-5393775-A | Administering a (2-chromanyl)alkylcarboxylic acid for disorders connected with peroxidation processes | ADIR ET COMPAGNIE (FR) | 1995-02-28 | — | — | US | disclosed |
| EP-0587499-A1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR ET COMPAGNIE (FR) | 1994-03-16 | — | — | EP | disclosed |