Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540485 | 0.89 | PARP1 (0.41) | MAPTHTTPARP1GPR84GSK3B | |
| SCHEMBL9373258 | 0.86 | PARP1 (0.43) | MAPTHTTPARP1GPR84GSK3B | |
| SCHEMBL8542673 | 0.86 | PARP1 (0.39) | MAPTHTTPARP1GPR84GSK3B | |
| SCHEMBL8544096 | 0.85 | PARP1 (0.46) | MAPTHTTPARP1GPR84GSK3B | |
| SCHEMBL9423818 | 0.85 | PARP1 (0.38) | MAPTHTTPARP1GPR84GSK3B | |
| SCHEMBL9432726 | 0.84 | PARP1 (0.41) | MAPTHTTPARP1GPR84GSK3B | |
| SCHEMBL9052175 | 0.82 | MAPT (0.59) | MAPTHTTPARP1GSK3BTSHR | |
| SCHEMBL9310425 | 0.81 | PARP1 (0.38) | MAPTHTTPARP1GPR84GSK3B | |
| SCHEMBL9310820 | 0.79 | SMN1; SMN2 (0.32) | MAPTHTTPARP1GPR84GSK3B | |
| SCHEMBL8540141 | 0.79 | PARP1 (0.43) | MAPTHTTPARP1GPR84GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497150-B1 | Angiotensin II receptor blocking 2,3,6-substituted quinazolones | AMERICAN CYANAMID CO (US) | 1998-03-18 | — | — | EP | claimed |
| CN-1066847-A | Angiotensin-ii receptor blockers 2,3,6 quinazolinones that replace | AMERICAN CYANAMID CO (US) | 1992-12-09 | — | — | CN | claimed |
| EP-0497150-A1 | Angiotensin II receptor blocking 2,3,6-substituted quinazolones | AMERICAN CYANAMID COMPANY (US) | 1992-08-05 | — | — | EP | claimed |
| US-5405849-A | Treating hypertension, congestive heart failure | AMERICAN CYANAMID COMPANY (US) | 1995-04-11 | — | — | US | disclosed |
| US-5358951-A | Treating hypertension, congestive heart failure | AMERICAN CYANAMID COMPANY (US) | 1994-10-25 | — | — | US | disclosed |
| US-5294611-A | Hypotensive, congestive heart failure | AMERICAN CYANAMID COMPANY (US) | 1994-03-15 | — | — | US | disclosed |
| US-5292734-A | Angiotensin II receptor blocking 2,3,6 substituted quinazolinones | AMERICAN CYANAMID COMPANY (US) | 1994-03-08 | — | — | US | disclosed |
| US-5290780-A | Hypotensive agents; congestive heart failure | AMERICAN CYANAMID CO. (US) | 1994-03-01 | — | — | US | disclosed |
| US-5288720-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1994-02-22 | — | — | US | disclosed |
| US-5284852-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| US-5284853-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| CN-1066847-A | Angiotensin-ii receptor blockers 2,3,6 quinazolinones that replace | AMERICAN CYANAMID CO (US) | 1992-12-09 | — | — | CN | disclosed |