Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539631 | 0.91 | SLC6A2 (0.65) | SLC6A2SMN1; SMN2 | |
| SCHEMBL8539715 | 0.89 | SLC6A2 (0.71) | SLC6A2 | |
| SCHEMBL8539243 | 0.86 | SLC6A2 (0.54) | SLC6A2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9671760 | 0.83 | SLC6A2 (0.59) | SLC6A2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8539625 | 0.83 | SLC6A2 (0.62) | SLC6A2NPC1RAB9A | |
| SCHEMBL8538709 | 0.82 | SLC6A2 (0.70) | SLC6A2ALDH1A1 | |
| SCHEMBL9738329 | 0.82 | SLC6A2 (0.69) | SLC6A2 | |
| SCHEMBL8539718 | 0.81 | SLC6A2 (0.65) | SLC6A2 | |
| SCHEMBL8539627 | 0.81 | SLC6A2 (0.60) | SLC6A2 | |
| SCHEMBL8539629 | 0.81 | SLC6A2 (0.60) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102891-A | Useful for treating various memory dysfunctions such as alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-04-07 | — | — | US | claimed |
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | disclosed |
| US-5102891-A | Useful for treating various memory dysfunctions such as alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0468401-A2 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-01-29 | — | — | EP | disclosed |